Welcome to the new look for CHI’s website. Our goal is to make information easier to find; if you have any issues or questions during the initial transition stage, please contact us.

CHI is a leading nonprofit dedicated to improving the lives of children and adults living with Congenital Hyperinsulinism (HI).

CHI provides a world of information, resources, and support to the HI community. CHI advocates on behalf of patients for better treatments and access to care. CHI is dedicated to increasing awareness of the disorder as it leads to more timely diagnosis and the best outcomes for patients. CHI supports medical research for improved therapies, potential cures, and timely diagnosis. CHI works globally because we are stronger as an international community. Cooperation across borders fosters important advances in medicine.

HI is a life-threatening disorder that causes dangerously low blood sugar levels. Prolonged or severe low blood sugar can cause seizures, brain damage, and even death. We hope you will partner with us to prevent damage and death, search for better treatments, and improve the quality of life for all HI patients.



International Guidelines for hyperinsulinism
NEW: The first-ever international hyperinsulinism guidelines have been published and are now available to the public! These guidelines are a collaboration of work by HI experts around the world, including many who are a part of the CHI Collaborative Research Network and Tai Pasquini of the CHI staff. Patient and caregiver representatives of the CHI Congenital Hyperinsulinism Collaborative Research Network provided the patient perspective. These guidelines are available free of charge and can be downloaded and shared with your care team. The new recommendations include:

  • Diagnosis
  • Medical Management
  • Surgical Management
  • Discharge Planning
  • Longterm Management of Patients with Hyperinsulinism

And more! Find the full guidelines by clicking here.


Open Hyperinsulinism Genes Project: Increasing Access to Genetic Testing

In 2018, Congenital Hyperinsulinism International partnered with researchers at the University of Exeter to fund the Open Hyperinsulinism Genes Project, an international genetic testing program. As a part of our joint initiative, CHI covers the costs of genetic testing for individuals who would otherwise be unable to receive genetic screening, regardless of their location in the world. This partnership is helping to ensure that there are no barriers for individuals diagnosed with this condition. You can find out more information on this exciting program here.

Hyperinsulinism Genes referrals map



CHI At A Glance, as of January 2024

We are incredibly grateful for another year of the global congenital hyperinsulinism (HI) community staying strong together to improve the lives of people living with the condition.

Whether you originally connected with us many years ago or just yesterday, we appreciate all you do to support the work of Congenital Hyperinsulinism International (CHI). You help us continue to work on advancing research for better treatments and cures, raising awareness of HI to prevent brain damage and death, and being there for HI families every step of the way.

2023 has been a very busy and productive year; view the 2023 HI-lights of the Year here.


Share